Ambient Air Pollution and the Risk of Childhood-onset Inflammatory Bowel Disease

This presentation will summarize the results from a study investigating the effects of ambient air pollution on the risk of developing pediatric-onset IBD using Ontario administrative health data. In-utero and childhood residential exposures to nitrogen dioxide (NO2), fine particulate matter (PM2.5) and ozone (O3) were evaluated in terms of their potential associations with IBD diagnosed before the age of 18. Other environmental factors, such as residential exposure to greenness as well as several maternal and individual-level factors were also considered as potential confounders and effect modifiers of these associations.